AGO Recommendations for the Diagnosis and Treatment of Patients with Advanced and Metastatic Breast Cancer: Update 2015.

Level of Evidence, LoE; www.cebm.net [1]) and ii) their clinical relevance (AGO grades of recommendation) (table 1). All AGO Breast Committee members have declared their potential conflicts of interest. Here, we present the 2015 update of these guidelines, focusing on relevant changes introduced this year. The full version of the updated 2015 slide set is available online as a PDF file [2] in English and German language. Moreover, a version for patients is also available at www.ago-online.de.